A recent study published in the journal Neurology suggests that high dose vitamin D supplementation could benefit people diagnosed with Multiple Sclerosis (MS)
HIGH DOSE VITAMIN D SUPPLEMENTATION LOWERS INFLAMMATORY T CELLS IN ADULTS WITH MULTIPLE SCLEROSIS
Researchers from Johns Hopkins University and colleagues tested the effects of vitamin D supplementation in a double-blind study involving 40 relapsing-remitting MS patients. One group of subjects received 10,400 (IU) and another received 800 IU vitamin D for six months. Serum levels of 25-hydroxyvitamin D were measured at the beginning of the study and at three and six months.
The serum vitamin D level of subjects taking the higher dosage increased by an average of 34.9 ng/ml, but only increased 6.9 ng/ml in the low dose group by the end of the study. In the group taking the higher vitamin D dosage, the proportion of pro-inflammatory T cells decreased, indicating a reduction in the severity of their disease.
More research is needed to confirm these findings, but the researchers were optimistic that these changes in inflammatory T cell responses could translate to a reduced severity of disease.
In the illustration: Autoimmune Disease. Multiple sclerosis – Immune cells attack the myelin sheath that surrounds nerve cells. Antibodies initiate myelin injury (macrophage activation).